Synthetic excitatory amino acids their preparation and pharmaceutical compositions containing them

摘要

The present invention provides novel compounds that affect certain excitatory amino acid receptors, and are useful in the treatment of neurological disorders and psychiatric disorders. The compounds have the formula CHEM wherein: X is (CH2)n; R2 is CO2R4 and R3 is hydrogen, or R2 is hydrogen and R3 is CO2R4; R1 and R4 are independently hydrogen, C1-C10 alkyl, C2-C10 alkenyl, aryl, or arylalkyl; and n is 1; or a pharmaceutically-acceptable salt thereof. cer