PHARMACEUTICAL COMPOSITIONS COMPRISING A SUPPORTED SACCHARIDE FOR THE TREATMENT OF TRAVELLERS' DIARRHEA CAUSED BY E. coli LT ENTEROTOXIN

摘要

A pharmaceutical composition useful in treating traveller's diarrhea and related conditions initiated by E. coli heat- labile toxin (LT) which composition comprises: (a) a saccharide sequence covalently attached to a pharmaceutically acceptable solid, inert support through a non-peptidyl compatible linker arm, wherein said saccharide sequence binds LT; and (b) a pharmaceutically acceptable carrier, wherein said composition is capable of being eliminated from the gastrointestinal tract.