PEPTIDE ELICITING THE NEUTRALISING ANTIBODIES FORMATION, AN IMMUNOGENIC AGENT, A VACCINE, A SYNTHETIC ANTIBODY, A DIAGNOSTIC ASSAY, THEIR USE AND METHOD FOR TESTING OCCURENCE OF PRRS VIRUS AT PIGS

摘要

The invention provides antigenic sites of PRRSV isolates. The antigenic sites are neutrahzmg, conserved, non-conserved and conformational, can elicit axntihodiee and are found on protein GP 4 and N encoded by ORF4- and ORF7 of PRRSV. The peptide sequences identified by the sites can be incorporated in vaccines directed against PRRS and in diagnostic tests for PRRS. Also, discriminating tests can be developed that can be used next to marker vaccines in programs designed to eradicate PRRS from pig herds.