METHOD FOR INDENTIFYING AND USING BIOSYNTHETIC OR REGULATORY GENES FOR ENHANCED PRODUCTION OF SECONDARY METABOLITES

摘要

Novel methods and compositions are provided for theenhanced production of secondary metabolites. Methods areprovided for identifying sequences which when transformedinto secondary metabolite producing hosts, enhance theproduction of secondary metabolite. The process isexemplified for penicillin. In addition, the P. chrysogenumacyltransferase gene has been isolated and sequenced.