GLYCOSPHINGOLIPIDS WITH A GROUP CAPABLE OF COUPLING IN THE SPHINGOID PORTION, THE PREPARATION AND USE THEREOF

摘要

The invention relates to the chemical modification of thesphingoid portions of glycosphingolipids. It has beenpossible by a series of reactions to introduce an aminogroup in the position of the carbon double-bond in thesphingoid portion after elimination of the long-chainaldehyde. Glycosphingolipids of the formula (2) and (3),where X and Y denote a group capable of coupling, aresuitable for coupling to other molecules, preferablyproteins. X preferably represents NH2, and Y preferably