首页> 外国专利> SYNERGETIC BLEND COMPOSITIONS BETWEEN AT LEAST ONE RXR SPECIFIC LIGAND AND AT LEAST ONE RAR-amp;#150; SPECIFIC LIGAND; USES THEREOF

SYNERGETIC BLEND COMPOSITIONS BETWEEN AT LEAST ONE RXR SPECIFIC LIGAND AND AT LEAST ONE RAR-amp;#150; SPECIFIC LIGAND; USES THEREOF

机译:至少一种RXR特定配体和至少一种RAR-特定配体之间的协同混合成分;使用其

摘要

The invention relates to the use of new combinations based on at least a first ligand having a selective activity for the RXRs receptors and at least a second ligand having a selective activity for the RAR-.alpha. Receptor, as principles active in, or for the manufacture of, pharmaceutical and / or dermatological compositions more particularly intended for modulating the proliferation and / or differentiation of a cellular system of the HL60 type, with the aim in particular of treating, systemically, promyelocytic leukemia acute.
机译:本发明涉及基于至少对RXRs受体具有选择性活性的第一配体和至少对RAR-α具有选择性活性的第二配体的新组合的用途。作为在药物和/或皮肤病学组合物中有活性或用于制造药物和/或皮肤病学组合物的原理的受体,其更特别地旨在调节HL60型细胞系统的增殖和/或分化,特别是目的是全身性治疗早幼粒细胞白血病急性。

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