Functionalised polymers for tissue engineering

摘要

Methods for functionalising polymers for tissue engineering are disclosed in which a polymer matrix is activated to bind to biological materials such as cells by covalently bonding a hydrophilic polymer to carboxy groups of a polymer matrix. The hydrophilic polymer comprises a ligand group or ligand group precursor which can bind to an extracellular matrix protein, thereby allowing cells to adhere and proliferate on the polymer matrix.