Method for determining the susceptibility of a niddm patient toward sulfonylureatherapy

摘要

This invention concerns a method for determining the susceptibility of a NIDDM patient toward sulfonylurea therapy comprising : a) obtaining a sample from a NIDDM patient, said sample comprising nucleic acid molecules containing the fragment of the SUR1 gene comprising the nucleotide in position -3 of intron 16, b) detecting the presence or the absence of the -3c allele in position -3 of intron 16, whereby the presence of at least one -3c allele identifies a NIDDM patient with a higher susceptibility toward sulfonylurea therapy. IMAGE