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Cancer treatment by photodynamic therapy, in combination with an immunoadjuvant

机译:通过光动力疗法结合免疫佐剂治疗癌症

摘要

Chitosan-derived biomaterials, and, more specifically, chitosan modified by the addition of a monosaccharide or oligosaccharide side chain to its free amino groups. The modified chitosan ("glycated chitosan") is preferably stabilized by reduction. In one particularly preferred embodiment, a galactose derivative of chitosan ("galacto-chitosan") is provided. The chitosan-derived biomaterials are useful in a myriad of biomedical applications, including as an immunoadjuvant in laser/sensitizer assisted immunotherapy.
机译:壳聚糖衍生的生物材料,更具体地说,是通过在其游离氨基上添加单糖或寡糖侧链进行修饰的壳聚糖。改性的壳聚糖(“糖基化壳聚糖”)优选通过还原来稳定。在一个特别优选的实施方案中,提供了壳聚糖的半乳糖衍生物(“半乳糖-壳聚糖”)。壳聚糖衍生的生物材料可用于多种生物医学应用中,包括作为激光/敏化剂辅助免疫疗法中的免疫佐剂。

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