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PROCESS FOR THE PREPARATION OF PAROXETINE ACETATE AND ANALOGUES THEREOF
PROCESS FOR THE PREPARATION OF PAROXETINE ACETATE AND ANALOGUES THEREOF
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机译:醋酸帕罗西汀的制备方法及其类似物
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摘要
The present invention relates to a new process for preparing pharmaceutically active compounds and intermediates therefor. The (-) trans isomer of 4-(4'-fluorophenyl)-3-(3',4'-methylenedioxyphenoxymethyl)-piperidine (paroxetine) is an important compound having antidepressant and anti-Parkinson properties. This compound is used in therapy as the hydrochloride salt to treat inter alia depression, obsessive compulsive disorder (OCD) and panic. There is described a process for the preparation of paroxetine acetate and analogues thereof.
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