The present invention relates to a method of desulfurizing a fossil fuel comprising organosulfur compounds. The methods comprises the steps of (1) contacting the fossil fuel with an aqueous phase comprising a microorganism which catalyzes the oxidative cleavage of carbon-sulfur bonds and sufficient nutrients for growth and/or reproduction of the microorganism, thereby forming an aqueous phase/fossil fuel mixture; (2) maintaining the aqueous phase/fossil fuel mixture under conditions which are suitable for the desulfurization of the fossil fuel, thereby producing a desulfurized fossil fuel; and (3) separating the desulfurized fossil fuel from the aqueous phase.
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