Mammalian nonhuman transgenic animal having a constitutive or inducible expression of the human endonexin II gene or its muteins or its fragments

摘要

The invention relates to a mammalian nonhuman transgenic animal liable to be infected by HBV and moreover liable to suffer from hepatocellular damage, caused by the constitutive or inducible expression of the human endonexin II gene or by the nucleotide sequence coding for its muteins or fragments, the said gene or the said nucleotide sequence being introduced into such a transgenic animal as a model for testing potential drugs.