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METHOD FOR INHIBITING CALCIFICATION OF ALDEHYDE-FIXED BIOPROSTHETIC MATERIALS
METHOD FOR INHIBITING CALCIFICATION OF ALDEHYDE-FIXED BIOPROSTHETIC MATERIALS
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机译:抑制乙醛固定的生物修复材料的计算方法
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摘要
A method for preparing collagenous biological tissues for use as implantable bioprosthetic material, and articles prepared thereby. The method generally comprises the steps of a) contacting the tissue with an aldehyde fixative to effect cross-linking of the connective tissue protein(s) and subsequently b) contacting the tissue with a polyglycidyl ether. The treatment of the crosslinked tissue with the polyglycidyl ether serves to mitigate the tissue's propensity to undergo calcification following implantation in the body.
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