4-IMIDOMETHYL-1-2'-PHENYL-2'OXOETHYL-PIPERIDINES AS SEROTONIN 5HT2-ANTAGONISTS, THEIR PREPARATION AND USE IN THERAPY

摘要

The present invention relates to a novel class of general formula (I) serotonin 5HT ₂ antagonists and pharmaceutically acceptable salts thereof, and their use for treating various diseases.;Wherein R is hydrogen, halogen, C ₁ -C ₄ alkyl, C ₁ -C ₄ alkoxy, -COF ₃ , -OH or -OCF ₃ , and A is one of the imide derivatives:;[Wherein R ₁ and R ₂ are each independently hydrogen, halogen C ₁ -C ₄ alkyl, C ₁ -C ₄ alkoxy, -CF ₃ , -OH or -OCF ₃ ]