首页> 外国专利> Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens

Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens

机译:通过与过敏原共享T细胞表位的抗原来调节过敏原敏感性的化合物

摘要

The present invention is related to a method for modulating the immune system of a mammal patient towards an allergen, which comprises the step of inducing a pre-sensitisation of the immune system of said patient towards an immunogen carrying at least one T cell epitope homologous and functionally similar to an epitope present on said allergen and deriving from a naturally-occurring antigen in order to modify the response of said patient to a further sensitisation to said allergen, allowing that the immune response towards the allergen is modulated and that no allergy towards said allergen will be developed in said patient.
机译:本发明涉及一种调节哺乳动物患者对变应原的免疫系统的方法,该方法包括以下步骤:诱导所述患者的免疫系统对携带至少一个与之同源的T细胞表位的免疫原预敏化。功能上类似于存在于所述变应原上并源自天然抗原的表位,以改变所述患者对所述变应原的进一步致敏的反应,从而允许针对变应原的免疫反应被调节并且对所述变应原无过敏所述患者体内会产生过敏原。

著录项

  • 公开/公告号GB0006437D0

    专利类型

  • 公开/公告日2000-05-10

    原文格式PDF

  • 申请/专利权人 LEUVEN RESEARCH & DEVELOPMENT V.Z.W.;

    申请/专利号GB20000006437

  • 发明设计人

    申请日2000-03-17

  • 分类号A61K47/48;A61K38/095;A61K38/42;A61K39;A61K39/35;A61P11/02;A61P11/06;A61P17;A61P37/08;

  • 国家 GB

  • 入库时间 2022-08-22 01:39:24

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