Chiral synthesis of 2-hydroxy carboxylic acids with a dehydrogenase

摘要

Inter alia, an enzyme, a 2-hydroxy carboxylic acid dehydrogenase, characterised in that it is obtainable from Lactobacillus delbrueckii ssp. Bulgaricus and in that it catalyses the production of (R) -hydroxy derivatives of 2-keto acids, which are unsubstituted in the 3- position, but which may be substituted in the 4-position or beyond is disclosed.