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Screening assays for compounds that inhibit membrane fusion- associated events
Screening assays for compounds that inhibit membrane fusion- associated events
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机译:筛选抑制膜融合相关事件的化合物的分析方法
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摘要
The present invention relates to peptides which exhibit potent anti- retroviral activity. The peptides of the invention comprise DP178 (SEQ ID:1) peptide corresponding to amino acids 638 to 673 of the HIV-1. sub. LAI gp41 protein, and fragments, analogs and homologs of DP178. The invention further relates to the uses of such peptides as inhibitory of human and non-human retroviral, especially HIV, transmission to uninfected cells.
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