ANALYSIS AND ESTIMATION OF PROTEIN FUNCTION SUBTYPE FROM PROTEIN SEQUENCE ALIGNMENT

摘要

PROBLEM TO BE SOLVED: To provide a method of analyzing and predicting a functional subtype from multiple protein sequence alignment about a new method of defining and predicting details about a function in large and various protein sequence families. SOLUTION: This method is for analyzing and predicting the functional subtype from the multiple protein sequence alignment. When a protein group classified into a subtype according to the alignment of enzyme specificity, etc., and function definition is given, in the method where a sequence profile is excluded and a position showing function difference is identified by analyzing positional entropy in the alignment.