首页> 外国专利> A compound N - 3 - 5 - (Hydroxy 1,4,5,6 - tetrahydro - 5 - hydroxy - 2 - Glicini is a historic building pirimidinil) amino benzoyl - 3 - (3 - 5 - Halo - Halo - 2 - hydroxyphenyl) - Beta AlanineComposicionfarmaceutica and Use thereof in the manufacture of a Medicament.

A compound N - 3 - 5 - (Hydroxy 1,4,5,6 - tetrahydro - 5 - hydroxy - 2 - Glicini is a historic building pirimidinil) amino benzoyl - 3 - (3 - 5 - Halo - Halo - 2 - hydroxyphenyl) - Beta AlanineComposicionfarmaceutica and Use thereof in the manufacture of a Medicament.

机译:化合物N-[3-[5-(羟基1,4,5,6-四氢-5-羟基-2-格利尼尼是具有历史意义的吡吡米尼)氨基]苯甲酰基]-3-(3-5-卤代-卤代-2-羟基苯基)-β丙氨酸组合物药用药物及其在药物生产中的用途。

摘要

The present Invention relates to compounds of formula (i) and the salts are acceptable for pharmaceutical use and isomers thereof, wherein X and y are the same or different Group Halo.R is Hydrogen or alkyl of C1 - 6.The pharmaceutical composition is also contieney reveals that its use in the manufacture of medicaments useful for treating conditions mediated by avbeta3 inhibition or antagonism of LAsintegrinas avbeta3.
机译:本发明涉及式(i)的化合物及其药学上可接受的盐及其异构体,其中X和y是相同或不同的卤代基团。R是氢或C 1-6的烷基。 contieney揭示了其在制造可用于治疗由avbeta3抑制或拮抗LAsintegrinas avbeta3介导的疾病的药物中的用途。

著录项

  • 公开/公告号AR018139A1

    专利类型

  • 公开/公告日2001-10-31

    原文格式PDF

  • 申请/专利权人 G.D. SEARLE & CO.;

    申请/专利号AR1999P100880

  • 发明设计人

    申请日1999-03-02

  • 分类号C07D239/16;A61K31/505;A61P35/00;A61P35/04;A61P19/02;

  • 国家 AR

  • 入库时间 2022-08-22 01:26:15

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