A - amino acid Derivatives arilaminoalquilamida where the carboxyl Group of the amino acid is replaced by a arilamino and amino N of amino acid form a Peptide Bond or pseudo peptidOr, their Preparation and their uses as Pharmaceutical Product utles as inhibitors of lacatepsina K.

摘要

The Invention provides amino acids arilaminoalquilamidas, where the carboxyl Group of the c-terminal amino acid is replaced by a Substituent arilanoalquilamino,And in which the nitrogen atom of the Amine forms a Peptide Bond or seudopeptido optionally comprises in addition a Linker methylene - heteroatom,Additional or a heteroatom, through which is directly substituted aryl, alkyl alquenilo Lower, Lower, Lower alquinilo, or heterociclilo,Or A physiologically acceptable Salt or Ester and dissociable from the same, including compounds of formula I,Or A physiologically acceptable Salt or Ester thereof.