Pharmaceutical composition comprising a compound derivadode imidazo 1,2-b piridazin or 1,2,4-triazole - 1,5-b - piridazincompuestos, its pro Drug and preparation procedures of compoundsUseful for the Treatment or prevention of Asthma, Allergic conjunctivitis, allergic rhinitis, Chronic urticaria and atopic dermatitis.

摘要

A Pharmaceutical composition for preventing or treating Allergic Skin Diseases such as Contact Dermatitis, pruritus, Dry dermatitis, acute urticaria and itching,Comprising a compound of formula I,Where aR1 and ar2 are independently an Aromatic group which can be replaced and aR1 and ar2 condensate can form a cyclic Group with an adjacent Atom C; The Ring B is a heterOciclo containing n can be replaced; X and y are the same or different, and are independently a Link, an o Atom, S (o) P) p = integer from 0 to 2),NR4 where R4 is a H Atom or a Lower alkyl group,Lower linear Hydrocarbon group or a Bivalent can contain 1 to 3 heroatomos Bivalent Hydrocarbon Group and the lower linear can be replaced; a is an Atom or CR7 is where R7 nA H Atom, a Halogen Atom, a Hydrocarbon which can be replaced, an acyl group or a hydroxyl group which can be replaced; r1R2 and R3 are the same or different, and are independently an H Atom, a Halogen Atom, a Hydrocarbon group which can be replaced,An acyl group or a hydroxyl group which can be replaced; R8 is a H Atom, a hydroxyl group which can be replaced by Lower alkyl group or a carboxylic acid,On condition that a heterocycle containing n represented by a heterocycle Ring B is not represented by the formula (a).