Compounds derived from piperidin-4-yl (piperidin-4-yl (piperidin-1-yl - 4 - substituted) - 1 - replaced, Pharmaceutical Composition and Pharmaceutical Kit, useful in the treatment of cognitive disorders,As Alzheimer's disease.

摘要

Amide Derivatives of piperidine compounds 1,4 - disustituida of formula or a Salt, Ester or pharmaceutically acceptable solvate thereof, where Q and each q1son - ch =,Or one of Q and Q1 is - and the other is - ch = n =; y and Z are - C (R5) or one of y and Z = - C = (R5) and the other is - n =; r1 is 1 to 3 substituents selected from h,Halogen and alcosir2 and R5 are 1 to 3 substituents selected from h, halogen,Alkyl and alkoxy; R3 and R4 are H or alkyl (C1 - C6) are Muscarinic antagonists useful in the treatment of cognitive disorders such as Alzheimer's disease.Also described are Pharmaceuticals compositions and preparation methods.