BIFUNCIONAL DERIVATIVES OF UROKINASE WIHT IMPROVED FIBRINOLYTIC ACTIVIY AND THROMBIN INHIBITING ACTIVITY

摘要

Bifunctional urokinase variants possessing improved fibrinolytic properties and thrombin inhibitory activities, plasmids used in the production of these polypeptides, as well as thrombolytic agents containing one of the bifunctional urokinase variants as active ingredient are described.