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Synergistic effects of amlodipine and atorvastatin or Atorvastatin metabolite as a basis for Combination Therapy

机译:氨氯地平与阿托伐他汀或阿托伐他汀代谢物的协同作用作为联合治疗的基础

摘要

Refers to a composition comprising amlodipine besylate); (b) a Salt of hemicalcio Atorvastatin or Atorvastatin Hydroxylated metabolite.The composition has a synergistic Antioxidant effect on Lipid peroxidation in low-density lipoproteins and Membrane vesicles enriched with polyunsaturated fatty acidsAnd may be useful to reduce the risk of Heart and artery disease such as hypertension, hyperlipidemia, atherosclerosis, arteriosclerosis, myocardial infarction,Congestive heart failure, stroke and angina pectoris, Lowers blood pressure, reduces Lipid concentrations
机译:指包含苯磺酸氨氯地平的组合物; (b)hemicalcio Atorvastatin或Atorvastatin羟化代谢产物的盐,该组合物对富含多不饱和脂肪酸的低密度脂蛋白和膜囊泡中的脂质过氧化具有协同抗氧化作用,可能有助于降低心脏病和动脉疾病的风险,例如高血压,高脂血症,动脉粥样硬化,动脉硬化,心肌梗塞,充血性心力衰竭,中风和心绞痛,降低血压,降低血脂浓度

著录项

  • 公开/公告号PE00552001A1

    专利类型

  • 公开/公告日2001-01-30

    原文格式PDF

  • 申请/专利权人 MASON R. PRESTON;

    申请/专利号PE20000000374

  • 发明设计人 MASON R. PRESTON;

    申请日2000-04-19

  • 分类号A61K31/445;A61K31/40;C07D207/34;C07D211/78;

  • 国家 PE

  • 入库时间 2022-08-22 01:24:15

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