compositions useful for transferring therapeutically active polynucleotides into a target cell and its use in gene therapy.

摘要

The present invention relates to a composition for transferring at least a therapeutically active substance into the interior of a target cell. Said composition is characterized by comprising a mixture of at least one substance therapeutically active, and at least one polar compound selected from a group SPECIFIC COMPOUNDS polar aprotic. This substance is preferably a therapeutically active polynucleotide, AND POLAR COMPOUND IS DPSO, WHICH INCREASES THE CAPACITY TO BE TRANSFERRED TO polynucleotide inside the cells. The compositions according to the invention can be used as a medicament diagnostic, therapeutic, prophylactic or VACCINATION FOR TREATING THE HUMAN BODY OR ANIMAL BY GENE THERAPY.