Enzymatic resolution of organic acid enantiomeric mixtures consists of reaction with an apolar organic solvent and alcohol with lipase based catalysis

摘要

The enzymatic resolution of organic and enantiomeric mixtures comprises reaction of e.g. (R.S)2-(4-isobutyl phenyl)propionic acid and (R.S)2-(3-benzoylphenyl)propionic acid in an apolar organic solvent, for resolution with an alcohol in the presence of a biocatalyst. EMBODIMENT - The biocatalyst is one or more lipases based on e.g. Fusarium oxysporum and Arthroderma ciferrii groups of microorganisms.