CLONING AND EXPRESSION OF HUMANIZED MONOCLONAL ANTIBODIES AGAINST HUMAN INTERLEUKIN-4

摘要

Monoclonal antibodies are providedwhich are specific for human interleukin-4.Also provided are complementary DNAswhich-encode the heavy and light chainvariable regions of such monoclonal antibodiesand complementarily determining regionsfrom such DNAs; and kits and methods fordetecting; measuring and immunopurifyinghuman intecleukin-4; and for blocking thebiological activity of human interleukin-4.