CANCER METASTASIS INHIBITOR CONTAINING A STREPTOCOCCUS AGALACTIAE IA TYPE OR IB TYPE SURFACE POLYSACCHARIDE AS A MAIN INGREDIENT

摘要

The present invention relates to the technologyfor inhibiting the cancer metastasis, and is aimed at theprovision of a pharmaceutical composition foreffectively inhibiting the metastasis of the cancer.A cancer metastasis inhibitor according to the presentinvention is characterized by containing a sugar chainseparated from a surface of a Streptococcus agalactiaeIa type or Ib type as a main ingredient. Since the surfacesugar chains of the Streptococcus agalactiae Ia type orIb type have structures similar to surface sugar chainsof the cancer cells, the former surface sugar chainsadhere to E-selectin appearing in an intravascularendothelial cell, competitively inhibit the adhesionbetween intravascular endothelial cells and the cancercells, and effectively prevent of the metastasis of thecancer, when the sugar chains exist in blood of a patient.