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Prevention of atherosclerosis and undesired blood clotting by reducing von willebrand factor
Prevention of atherosclerosis and undesired blood clotting by reducing von willebrand factor
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机译:通过减少血管性假血友病因子预防动脉粥样硬化和不希望的凝血
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摘要
This invention provides methods and compositions for treating and preventing atherosclerosis other undesired blood clotting. The methods for treating and preventing atherosclerosis and related conditions involve administering to a mammal an agent that reduces activity of an ST3Gal IV sialyltransferase, which results in enhanced clearance of von Willebrand Factor (vWF) from the mammal.
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