GENE ENCODING NOVEL ADP-RIBOSYLATION FACTOR (ARF)-LIKE PROTEIN

摘要

By an oligocap method originally developed for isolating full-length cDNA, a plural number of full-length cDNAs are isolated from a cDNA library originating in a 10-week old human fetal tissue. Among these cDNAs, a clone (C-HEMBA1001174) encoding a novel ARF-like protein is isolated. It is assumed that C-HEMBA1001174 has biological functions of intracellular vesicular transport, etc. Thus, it is expected as usable as an important target in diagnosing diseases in association with abnormality in these functions and developing drugs for preventing or treating these diseases.