INOSITOL-CONTAINING HEXASACCHARIDES, THEIR SYNTHESIS AND THEIR USES

摘要

The application relates to the design and synthesis of novel hexasaccharides of general formula (I), wherein: each R is independently selected from hydrogen, an alkyl or substituted alkyl group, an acyl or substituted acyl group, a phosphate group (PO3- or PO3H for instance) or a protecting group, or two of the R groups may be cyclic phosphate; NX group represents N3; or in the NX group, X represents one or more groups independently selected from hydrogen, alkyl or substituted alkyl, acyl or substituted acyl; NY represents a phthalimido group (NPht) or N3; or in the NY group, Y represents one or more groups independently selected from hydrogen, alkyl or substituted alkyl, acyl or substituted acyl; or a salt or derivative of said compound. Methods for synthesizing the compounds and their uses are also disclosed.