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PROTEINS CAPABLE OF TRIGGERING G2/M TRANSITION AND OF INTERACTING WITH CDC2- AND CYCLIN B

机译:能够触发G2 / M转变并与CDC2-和周期蛋白B相互作用的蛋白

摘要

A DNA sequence according to the invention contains (a) a sequence as shown in SEQ ID NO.1 or 2, (b) a sequence which encodes the same protein as (a) but is degenerate as a result of the genetic code, (c) a sequence hybridizing under stringent conditions to the sequences of (a) and/or (b), (d) a genomic sequence containing the sequence of (a), (b) or (c) and further containing one or more introns, or (e) a sequence which differs from (a), (b), (c) or (d) due to its origin from a different species. A protein according to the invention is encoded by such DNA sequence and can be used for inducing oocyte maturation and/or promoting cell division and/or differentiation and/or proliferation, in a pharmaceutical compostion or as diagnostic agent. IMAGE
机译:根据本发明的DNA序列包含(a)如SEQ ID NO.1或2所示的序列,(b)编码与(a)相同的蛋白质但由于遗传密码而简并的序列,( c)在严格条件下与(a)和/或(b)的序列杂交的序列,(d)含有(a),(b)或(c)的序列并进一步含有一个或多个内含子的基因组序列,或(e)由于源自不同物种而不同于(a),(b),(c)或(d)的序列。本发明的蛋白质由这种DNA序列编码,并且可以在药物组合物中或作为诊断剂用于诱导卵母细胞成熟和/或促进细胞分裂和/或分化和/或增殖。 <图像>

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