Remedies/Preventives for frequent urination/Urinary incontinence and Tropone derivatives

摘要

The present invention relates to novel compounds having therapeutic, prophylactic and Trojan phone skeleton of urinary frequency, urinary incontinence that the acceptable salt of the compound or its pharmacologically having a Trojan skeletal phone as an active ingredient. Compounds having a Trojan phone skeleton wherein the pharmacological action is represented by the general formula (1), for, e.; (The above formula, and R ₁ and R ₂ are hydrogen or a lower alkyl group, R ₃ is -OR a or -NR _2, R _4, R ₅ and R ₁₂ are each hydrogen or a lower alkyl group, X is a nitrogen atom or a CH a, Z represents a -CHAr _2, unsubstituted or substituted phenyl group and the like, respectively, m represents 1 or 2); Further, Z is a novel compound, and except for the compound ₂ -CHAr.