/ METHOD FOR DEVELOPING TESTING AND USING ASSOCIATES OF MACROMOLECULES AND COMPLEX AGGREGATES FOR IMPROVED PAYLOAD AND CONTROLLABLE DE/ASSOCIATION RATES

摘要

Variety of amphiphilic polymer (polypeptide, protein, etc.) or other chain molecules (e. G., Partially hydrophobized a suitable polynucleotide or a polysaccharide such as a) a polar and / or charged amphiphilic materials of the present invention, if necessary modified It made of a mixture of free and suspension base or a suitable principle and process for the growth of the combination of and to form an extended surface aggregates that can be supported, testing, preparation and use. After combining the described methods and some chain molecule representing the active or useful features may be used for the aggregate, which for example in the field of delivery or conditions of the drug studies or in vivo / hydrolysis using in vitro or vivo conditions it is suitable. Specific examples, (combined) and insulin, interferon, interleukin, nerve growth factor, calcitonin, and an immunoglobulin, such as cyst form of the liquid-containing mixture, and consisting of a lipid is described.