NOVEL STRESS-REGULATORY PROTEIN, THIF, BINDING TO THIOREDOXIN

摘要

PURPOSE: Provided is a novel regulatory protein, THIF, which inhibits the activity of thioredoxin and enhances cell death by binding to thioredoxin, an intracellular reducing material. The THIF can be used in regulating stress, and is thus useful to biotechnology and medical science. CONSTITUTION: A THIF(thioredoxin-interacting factor) gene has base sequence represented by sequence No. 1, No. 2, No. 3 or No. 4 and expresses THIF protein which binds to thioredoxin.