Aromatic-linked Polyamine Macrocyclic Compounds Having Anti-HIV Activity

摘要

Formula: Z-R-A-R'-Y linked cyclic polyamines show high activity and low toxicity against HIV in in vivo tests.;Wherein Z and Y are each a cyclic polyamine group, A is an aromatic or heteroaromatic group, and R and R 'are each an alkylene chain or a hetero atom containing chain.;New compounds and pharmaceutical compositions are claimed.