首页> 外国专利> STRAIN OF BACTERIUM PSEUDOMONAS AERUGINOSA 5142 USED FOR PREPARING VACCINE AGAINST FUR WILD ANIMALS PSEUDOMONOSIS

STRAIN OF BACTERIUM PSEUDOMONAS AERUGINOSA 5142 USED FOR PREPARING VACCINE AGAINST FUR WILD ANIMALS PSEUDOMONOSIS

机译:铜绿假单胞菌514 2 菌株用于制备抗野生野生动物肺炎疫苗

摘要

FIELD: biotechnology, veterinary science. SUBSTANCE: invention relates to production of vaccine preparations against pyocyanic infection in wild animal, preferably in polar foxes and foxes. Strain of bacterium Pseudomonas aeruginosa 5142 is deposited in collection of strains that are pathogens of diseases in fur wild animals of museum of bacterial and viral cultures of Science-Research institute of fur farming and rabbit breeding (NIIPZK) named for V. A. Afanasiev and has registration number 5142. Strain relates to serovariant 06. Strain is cultured in Marten's broth or synthetic medium at 32 C for 18-20 h at constant shaking. After control of grown culture for toxicogenicity and proteolytic activity bacterial mass is separated and inactivated and then aluminium hydroxide is added as an adjuvant. Invention ensures to prevent the concealed loss in reproduction of fur wild animals in farms with pyocyanic infection being independently of serological pattern of pathogen. EFFECT: strain indicated above, enhanced effectiveness of vaccine. 3 ex
机译:领域:生物技术,兽医学。物质本发明涉及在野生动物中,优选在极地狐狸和狐狸中抗氰化感染的疫苗制剂的生产。铜绿假单胞菌(Pseudomonas aeruginosa)514 2 菌株被藏在毛皮养殖和兔子繁殖科学研究所细菌和病毒文化博物馆的毛皮野生动物中作为病原体的菌株中以VA Afanasiev命名,注册号为514 2 。菌株涉及血清变异体06。在恒定振荡下,将菌株在32℃的Marten肉汤或合成培养基中培养18-20h。在控制生长的培养物的毒性和蛋白水解活性之后,分离并灭活细菌团,然后加入氢氧化铝作为佐剂。本发明确保了在患有蓝光感染的农场中防止毛皮野生动物繁殖的隐性损失,而与病原体的血清学模式无关。效果:上述菌株,增强了疫苗的有效性。 3前

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