STRAIN OF BACTERIUM PSEUDOMONAS AERUGINOSA 500₂ USED FOR PREPARING VACCINE AGAINST FUR WILD ANIMAL PSEUDOMONOSIS

摘要

FIELD: biotechnology, veterinary science. SUBSTANCE: invention relates to production of vaccine preparations against pyocyanic infection in fur wild animals, mainly in polar foxes and foxes. Strain of bacterium Pseudomonas aeruginosa is deposited in collection of strains that are pathogens of diseases in fur wild animals of museum of bacterial and viral cultures of Science-Research institute of fur farming and rabbit breeding (NIIPZK) named for V. A. Afanasiev and has registration number 500₂. Strain relates to serovariant 09. Strain is cultured in Marten's broth or synthetic medium at 32 C for 18-20 h at shaking. After control of grown culture for toxicogenicity and proteolytic activity bacterial mass is separated and inactivated followed by addition of aluminum hydroxide as an adjuvant and packaged. Invention ensures to prevent the concealed loss in reproduction of fur wild animals in farms with pyocyanic infection being independently of serological pattern of pathogen. EFFECT: strain indicated above, enhanced effectiveness of vaccine. 3 ex