首页> 外国专利> STRAIN OF BACTERIUM PSEUDOMONAS AERUGINOSA 5291 USED FOR PREPARING VACCINE AGAINST FUR WILD ANIMALS PSEUDOMONOSIS

STRAIN OF BACTERIUM PSEUDOMONAS AERUGINOSA 5291 USED FOR PREPARING VACCINE AGAINST FUR WILD ANIMALS PSEUDOMONOSIS

机译:铜绿假单胞菌529 1 菌株用于制备抗野生野生动物肺炎疫苗

摘要

FIELD: biotechnology, veterinary science. SUBSTANCE: invention relates to production of vaccine preparations of pyocyanic infection in fur wild animals, preferably in polar foxes and foxes. Strain of bacterium Pseudomonas aeruginosa 5291 is deposited in collection of strains that are pathogens of diseases in fur wild animals of museum of bacterial and viral cultures of Science-Research institute of fur farming and rabbit breeding (NIIPZK) named for V. A. Afanasiev and has registration number 5291. Strain relates to serovariant 03. Strain is cultured in Marten's broth or synthetic medium at 32 C for 18-20 h at constant shaking. After control of grown culture for toxicogenicity and proteolytic activity bacterial mass is separated and inactivated and then aluminum hydroxide is added as an adjuvant and packaged. Invention ensures to prevent the concealed loss in reproduction of fur wild animals in farms with pyocyanic infection being independently of serological pattern of pathogen. EFFECT: strain indicated above, enhanced effectiveness of vaccine. 3 ex
机译:领域:生物技术,兽医学。发明领域本发明涉及在毛皮野生动物中,优选在极地狐狸和狐狸中产生氰化物感染的疫苗制剂的生产。铜绿假单胞菌529 1 菌株被保存在毛皮农牧科学研究院细菌和病毒文化博物馆的野生动物的病原体菌株中以VA Afanasiev命名,注册号为529 1 。菌株与血清变种03有关。在恒定振荡下,将菌株在32℃的Marten肉汤或合成培养基中培养18-20小时。在控制生长的培养物的毒性和蛋白水解活性后,分离并灭活细菌团,然后加入氢氧化铝作为佐剂并包装。本发明确保了在患有蓝光感染的农场中防止毛皮野生动物繁殖的隐性损失,而与病原体的血清学模式无关。效果:上述菌株,增强了疫苗的有效性。 3前

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