首页>
外国专利>
heparin binding epidermal growth factor with homology to mitogeninduced liver (egf)
heparin binding epidermal growth factor with homology to mitogeninduced liver (egf)
展开▼
机译:肝素结合表皮生长因子与有丝分裂原诱导的肝(egf)具有同源性
展开▼
页面导航
摘要
著录项
相似文献
摘要
PCT No. PCT/US91/07691 Sec. 371 Date Jun. 15, 1993 Sec. 102(e) Date Jun. 15, 1993 PCT Filed Oct. 16, 1991Disclosed are heparin binding mitogens which include an epidermal growth factor-homologous segment (HB-EHM). These factors stimulate proliferation of fibroblast cells, epithelial cells, and smooth muscle cells, but not endothelial cells. Also disclosed are isolated antibodies that recognize, and purified nucleic acids that encode, the above growth factors as well as isolated polypeptides, vectors containing such nucleic acids, and cells harboring such vectors. Growth factors of this invention may be used for accelerating the rate of wound healing, for the in vitro culture of HB-EHM-responsive cells, and for the identification of antagonists to HB-EHM.
展开▼