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Human cyclin I and genes encoding same

机译:人类细胞周期蛋白I及其编码基因

摘要

This invention relates to a novel protein having a high degree of homology to the amino acid sequence of the so-called cyclin box which is characteristic of cyclins: they are herein referred to as “human cyclin I” or “human cyclin I protein.” Further, the invention relates to a gene encoding their amino acid sequences and the protein: the gene is referred to as “gene encoding human cyclin I” or “human cyclin I gene.” Also, the invention relates to expression vector into which the human cyclin I gene is incorporated as well as to a transformant into which the vector is introduced. Still further, the invention relates to a recombinant protein obtained by growing the transformant. In addition, the invention relates to a novel neuron-marking method using an anitisense nucleotide of the gene as probe. Furthermore, the invention relates to method for screening cancer cell using the human cyclin I gene.
机译:本发明涉及一种新型蛋白,它与细胞周期蛋白的特征即所谓的细胞周期蛋白盒的氨基酸序列具有高度的同源性:它们在本文中被称为“人细胞周期蛋白I”。或“人细胞周期蛋白I蛋白”。此外,本发明涉及编码其氨基酸序列和蛋白质的基因:该基因被称为“编码人细胞周期蛋白I的基因”。或“人细胞周期蛋白I基因”。另外,本发明涉及其中掺入了人细胞周期蛋白I基因的表达载体以及其中引入了该载体的转化体。更进一步,本发明涉及通过使转化体生长而获得的重组蛋白。另外,本发明涉及使用基因的反义核苷酸作为探针的新型神经元标记方法。此外,本发明涉及使用人细胞周期蛋白I基因筛选癌细胞的方法。

著录项

  • 公开/公告号US6218115B1

    专利类型

  • 公开/公告日2001-04-17

    原文格式PDF

  • 申请/专利权人 SUMITOMO ELECTRIC INDUSTRIES LTD.;

    申请/专利号US19980054492

  • 发明设计人 TAKESHI NAKAMURA;

    申请日1998-04-03

  • 分类号C12Q16/80;C07H210/20;C07H210/40;C12N150/00;

  • 国家 US

  • 入库时间 2022-08-22 01:04:37

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