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Structure and expression of the biotin carboxylase subunit of heteromeric acetyl-CoA carboxylase
Structure and expression of the biotin carboxylase subunit of heteromeric acetyl-CoA carboxylase
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机译:异源乙酰辅酶A羧化酶生物素羧化酶亚基的结构和表达
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摘要
The gene encoding a biotin carboxylase subunit of heteromeric ACCase has been isolated and sequenced. The cDNA sequence and deduced amino acid sequence is set forth in FIG. 1 and has been accorded GenBank Accession No. L38260. By controlling expression of the gene of the present invention, carboxylation of acetyl-CoA to produce malonyl-CoA may be controlled. Thus, by introducing constructs of the gene of the present invention in sense or anti-sense orientation, carboxylation of acetyl-CoA to produce malonyl-CoA may be increased or decreased. Consequently, fatty acid synthesis in plants and seeds which depends on malonyl-CoA in the plastid may also be controlled.
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