Peptide having β1 integrin subunit-dependent cell adhesion regulating activity

摘要

Peptides capable of modulating beta 1 integrin subunit dependent cell adhesion which includes a C-terminal aromatic amino acid residue and an amino acid residue having a lipophilic alkyl side chain as the penultimate C-terminal residue are provided. These "LipAr" C-terminated peptides are typically capable of modulating the beta 1 integrin subunit dependent adhesion of cells, such as Ramos cells.