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Active component vector of liposome novel
Active component vector of liposome novel
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机译:脂质体小说的活性成分载体
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摘要
(57) this [summary] The present invention relates to a liposome vector of the active ingredient in powder form. And more particularly to the application of the drugs and their active ingredients susceptible to plasma degradation and / or digestion, such as proteins. Two classes of substances, the [internal aqueous gel as well as in the nucleus 5 classes of substances and Class 3 / or materials to any ,, the liposome vector of the active ingredient - sol phase transition at 37 ℃ or more, is selected from carrageenan and gelatin G1 class in combination carrageenans having characteristics different from the carrageenan G2 is selected in G1 for and are selected from cellulose, and] consists of a mixture of M (G2 and G1) capable of polymerizing different non-gelling agent at least two s made of a powder composition consisting essentially of unilamellar liposomes composed of external lipid phase composed of (a phospholipid) 4 Lipid. 20nm~1mm, has a diameter in the range of 20nm~500nm preferably the liposomes; formed the composition have an average molecular diameter of 10mm~1000mm, liposomes by the one or more forms of grain units has, trapped in the coating in a selected from the group consisting of thermo-reversible aqueous gels, dextrin or dehydrated equal to the internal nuclear aqueous gel, which is 10 16 ~ per gram of powder on average contains the external lipid phase or the internal nucleus and containing 10 18 liposomes, gelled at least one active ingredient.
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