Designates the imidazoriruporuhuirin metal complex as the monomer the porphyrin dimer

摘要

PROBLEM TO BE SOLVED: To obtain the subject new compound which has an allosteric function, is useful as an ingredient for artificial blood, and can additionally be expected as a position-selective oxygenating reagent and as a highly sensitive sensor for gas molecules such as oxygen, nitrogen monoxide and carbon monoxide. ;SOLUTION: A porphyrin dimer of formula I [M is Fe(II) or Co(II); Im is an imidazolyl group of formula II (R2 and R3 are each H or an alkyl) or the like; R1 is a substituted phenyl group of formula III (R5 is H, a halogen or the like; R6 is an alkyl, an aryl or the like; R7 is H, a halogen or the like)], for example, 5,10,15-tris(α,α,α-o-pivaloylaminophenyl)-20-imidazolyl iron (II) porphyrin dimer. The compound is obtained, for example, by reacting a compound of formula IV (R9 is H, a halogen or the like) with a compound of the formula: OHC-Im and pyrrole to synthesize a porphyrin compound, converting the nitro group of the synthesized porphyrin compound into an amino group, purifying a compound having a desired steric configuration from the obtained compounds, acylating the amino group of the purified compound, inserting a metal atom to the product, and then a the product.;COPYRIGHT: (C)2001,JPO