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Process for making optically active alpha-amino ketones and selected novel optically active alpha-amino ketones
Process for making optically active alpha-amino ketones and selected novel optically active alpha-amino ketones
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机译:制备光学活性α-氨基酮和选择的新型光学活性α-氨基酮的方法
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摘要
The invention includes selected novel optically active &agr;-ketones which either are themselves useful or are intermediates for the preparation of known ketomethylene pseudopeptides useful as antibiotics, antibiotic enhancers, or enzyme inhibitors. Further, the present invention provides a method for dehydrogenation/asymmetrical hydrogenation to obtain essentially pure antipodes of ketomethylene pseudopeptides having two chiral centers.
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