Use of diazepines for the preparation of medicaments for the treatment of Pathological States and diseases which is involved in at leastone of somatostatin receptors.Diazepines used in the medicine and preparation and Pharmaceutical composition containing them.

摘要

1. For the production of a drug for the treatment of a pathological or diseased condition involving at least one diazepine (1) receptor of a common formula, in which w represents a hydrogen atom or r-x-c (y) transmitter;R stands for arilo radical or heterosexual radical, while arilo radical and heterosexual radical are optionally replaced; x stands for an N-Z (CH2) formula radical, in which ZZ stands for a mixed link, NH, or s and n stand for one or more same or different groups, Select from the following atoms: a hydrogen atom, a hydroxyl atom, a halogenated radical, a lower tar and a lower nitrous oxide; R2A and r2b independently represent a dehydrogeno atom; a lower tar, a lower calcium or a lower tar containing optional tar, acyl chloride and tar, or a r21z21-en radical. This is the O, C (o) represented by z21,That's it.S. R21 represents a hydrogen atom, a matrix, a matrix, an atom below arilo or arilalquilo; R3 represents a hydrogen atom, a radical atom of halogenation, nitration or cyanogenation, a carbon atom, one to ten carbon atoms, one to ten carbon atoms, one to dienyl oxide, one to dienyl, one to dienyl, one to dienyl, arilo, arilalquilo, arilalquilo, Unorthodox or unorthodox, including selected asphalt, clay, asphalt, cyclopentyl, arilo and heteromorphic radicals; or r31z31 radicals, wherein Z31 represents o, C (or),That's it.R31s represents a hydrogen atom, a lower tar, arilo or a lower arilalquilo,Or a salt of this product, which is used to prepare a drug for the treatment of a disease or disease, involving one (or more) sleeping ketone receptor. Because there are many pathological impurities related to sleeping ketone, it is necessary to find compounds related to sleeping ketone receptor.These include the atoms in general equation (2), i.e. w represents the hydrogen atom or a formula base.