2.4 - disustituida triazine Derivatives, use thereof for preparing medicaments, Pharmaceutical compositions containing Same, Process for preparing them,And a method for preparing Said Derivatives.

摘要

This invention relates to the use of compound having formula (1) to N-oxides, to pharmaceutically acceptable addition salts, quaternary amines and their stereochemically isomeric forms in which -a1 = a2-a3 = a4- form unfeni lo, pyridinyl, pyrimidinyl, pyridazinyl opirazinyl with the vinyl group attached; n is 0 to 4 and where 5 is possible; R1 is hydrogen, aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6alkyloxycarbonyl; substituted C 1-6 alkyl or C 1-6 alkyloxy; C 1-6 alkylcarbonyl substituted; each R2 independently is hydroxy, halo, optionally substituted C 1-6 alkyl; C1-6 alkyl, C2-6 substituted alkenyl or C2-6 alkynyl,cicloalquilo C3-7 alquiloxi C1-6 alquiloxicarboniloC1-6 carboxilo ciano nitro amino mono o di (alquilo C1-6) amino polihalometilo polihalometiloxi polihalometiltio -S (3DO) pR4 -NH-S (3DO) NHNH2 -NHC (3DO) R4 -C -NH-NH-N=N- that is... -C (=O)-Choh...- yes.-S (3DO) - o -S (3DO) 2-1. Arilo is a phenyl subsit uido; used in the production of drugs for the treatment of people living with HIV (human immunodeficiency virus).