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VIIa factor inhibitors, a preparation process, a drug synthesis, and use it to make a drug that reduces the inflammatory response to blood clotting or cardiovascular disease, thrombopathy, or restorative disorders.
VIIa factor inhibitors, a preparation process, a drug synthesis, and use it to make a drug that reduces the inflammatory response to blood clotting or cardiovascular disease, thrombopathy, or restorative disorders.
This refers to compounds of Formula (1) in which R1, R2, R91, R92, R93, R94, R95, R96, R97, r, s and t have the meanings indicated in the claims. The compounds of Formula (1) are valuable pharmacologically active compounds. They exhibit a strong antithrombotic effect and are suitable, for example,For the treatment and prevention of thrombotic or restorative diseases. They are reversible inhibitors, which can be widely used in the inhibition treatment of the inhibition of the VIIa factors in the case of unexpected activities of the VIIa, or in the case of trying to inhibit the VIIa factors. In addition, the process (1) applied to the preparation of deformation compounds,2. Use it as, in particular, active ingredients in pharmaceutical synthesis and pharmaceutical preparations containing these ingredients;
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