首页> 外国专利> Use of a compound, use of a diastereoisomer in pure form or a mixture of diastereoisomers of the compound, compound, pharmaceutical composition, method for the treatment and prophylaxis of osteoporosis and related bone conditions, and method for the treatment of patients suffering from conditions pathological

Use of a compound, use of a diastereoisomer in pure form or a mixture of diastereoisomers of the compound, compound, pharmaceutical composition, method for the treatment and prophylaxis of osteoporosis and related bone conditions, and method for the treatment of patients suffering from conditions pathological

机译:化合物的用途,化合物的纯形式的非对映异构体或非对映异构体的混合物,化合物,药物组合物,骨质疏松症和相关骨病的治疗和预防方法以及病理性疾病患者的治疗方法

摘要

"USE OF A COMPOUND, USE OF A DIASTEREOISÈMERO IN PURE FORM OR A MIXTURE OF COMPOSITE, COMPOUND, COMPOSITION, PHARMACEUTICAL COMPOSITION, METHOD FOR THE TREATMENT AND PROPHYLAXIS OF OSTEOPOROSIS AND TREATMENT OF OSTEOPOROSIS, EASY TREATMENT OF OTHERSOUGH TREATMENTS, BETWEEN TREATMENT AND OTHERSEASY TREATMENT. PATHOLOGICAL CONDITIONS ". Compounds of formula (I) in which X represents hydrogen or hydroxy; Y represents oxygen or sulfur or oxidized sulfur selected from groups S (O) and S (0 ~ 2 ~); R ^ 1 ^ and R ^ 2 ^, which may be the same or different, represent hydrogen or a residue after removing 1 hydrogen atom from a saturated, straight, branched or cyclic C ~ 1 ~ -C ~ 6 ~ hydrocarbon or unsaturated; or R ^ 1 ^ and R ^ 2 ^, together with the carbon atom to which they are attached [marked with an asterisk in formula (I)], carrying the group X, form a C ~ 3 ~ -C ~ carbocyclic ring 8 ~; Q represents a di-radical residue after removing 2 hydrogen atoms from a straight, branched or cyclic, saturated or unsaturated C ~ 1 ~ -C ~ 8 ~ hydrocarbon; R 3 represents hydrogen or a residue after removing 1 hydrogen atom from a straight, branched or cyclic, saturated or masked C ~ 1 ~ -C ~ 6 ~ hydrocarbon being hydrolyzable in vivo; can be used for the preparation of a medicament for the treatment and / or prophylaxis of osteoporosis and related bone disorders.
机译:“使用化合物,以纯净形式或混合物形式使用非甾体二烯异构体,化合物,化合物,药物组合物,骨质疏松症的治疗和预防方法以及骨质疏松症的简便治疗,其他疗法的简便治疗, “病理条件”。式(I)的化合物,其中X代表氢或羟基; Y代表选自S(O)和S(0〜2〜)组的氧或硫或氧化硫; R ^ 1 ^和R ^ 2 ^可以相同或不同,表示从饱和的,直链,支链或环状的C〜1〜-C〜6〜烃或不饱和烃中除去1个氢原子后的氢或残基;或R ^ 1 ^和R ^ 2 ^,以及它们所连接的碳原子[在式(I)中标有星号],带有基团X,形成C〜3〜-C〜碳环8 〜; Q表示从直链,支链或环状,饱和或不饱和的C〜1〜-C〜8〜烃中除去2个氢原子后的双自由基残基; R 3表示氢或从可在体内水解的直链,支链或环状,饱和或掩蔽的C〜1〜-C〜6〜烃中除去1个氢原子后的氢或残基。可用于制备用于治疗和/或预防骨质疏松症和相关骨疾病的药物。

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